Estimating the infection fatality rate from SARS-CoV-2 in India
Abstract
There has been much discussion and debate around the underreporting of COVID-19 infections and deaths in India. In this short report we first estimate this underreporting factor for infections from publicly available data released by the Indian Council of Medical Research from national seroprevalence surveys. We then use a rigorous compartmental epidemiologic model to estimate the undetected number of infections and deaths. Both estimates qualitatively show that there is a large degree of 'covert infections' in India, with model-based estimated underreporting factor for infections as 11.11 (95% CI 10.71–11.47) and for deaths as 3.56 (95% CI 3.48–3.64). This implies approximately 91% of infections and 72% of deaths related to COVID-19 remain unreported in India. These estimates enable us to calculate the infection fatality rate (IFR) for India: if we rely on only reported deaths the IFR estimate is 0.13%, while taking underreporting of deaths into account, the IFR estimate is 0.46%. There is considerable variation in these estimates across states.